malignant syndrome in parkinson disease similar to severe infection

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ID: 129818
2017
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Abstract
A 70-year-old woman with Parkinson disease was admitted to the emergency department with altered consciousness, fever and convulsive movements without experiencing withdrawal from antiparkinsonian medication. Six hours after the emergency department visit, the patient had a hyperpyrexia (> 40°C) and a systolic blood pressure of 40 mmHg. There was no evidence of bacterial infection based on extensive workups. The patient was discharged without aggravation of Parkinson disease symptoms after treatment that included administration of dantrolene sodium, enforcement of continuous renal replacement therapy and cooling blankets. Malignant syndrome should be suspected if high fever occurs in Parkinson disease patients without evidence of a definitive infection.
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lee2017koreanmalignant Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Dong Hun Lee;Jeong Mi Moon;Yong Soo Cho
Journal korean journal of critical care medicine
Year 2017
DOI
10.4266/kjccm.2016.00087
URL
http://www.kjccm.org/upload/pdf/kjccm-2016-00087.pdf
Keywords
Fever dehydration critical care first aid

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