the efficacy of thai herbal prasaplai formula for treatment of primary dysmenorrhea: a short-term randomized controlled trial
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ID: 129717
2016
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Abstract
This study aims to compare the efficacy of pain relief between a specific Thai herbal Prasaplai formula (PPF) and placebo in patients with primary dysmenorrhea. Forty women with primary dysmenorrhea symptoms were randomized into two groups. The experimental group received PPF capsules 1000 mg orally three times per day before meals for three days starting from the first day of menstruation. The placebo group received placebo as the same dose and time. Average pain intensity from the first day to the third day of cycle significantly decreased in both groups (p<0.001), but with no statistically significant difference between groups. Using a pre- and posttreatment difference in NRS of at least 2, a greater proportion of patients in PPF group experienced pain relief compared to placebo during the first and second day of period. A greater proportion of PPF group also experienced no pain compared to the placebo group on day 1 and day 3 by using multidimensional scoring. The PPF demonstrates pain relief activity when used during menstruation in primary dysmenorrhea patients, with no adverse effects. However, further studies are needed in order to assess the value of PPF as a long-term prophylaxis for primary dysmenorrhea.
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| Reference Key |
vannabhum2016evidence-basedthe
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|---|---|
| Authors | ;Manmas Vannabhum;Sirikan Poopong;Thanyarat Wongwananuruk;Akarin Nimmannit;Ueamphon Suwannatrai;Chongdee Dangrat;Angkana Apichartvorakit;Suksalin Booranasubkajorn;Tawee Laohapand;Pravit Akaraserenont |
| Journal | ACS applied materials & interfaces |
| Year | 2016 |
| DOI |
10.1155/2016/2096797
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| URL | |
| Keywords |
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