additive global cerebral blood flow normalization in arterial spin labeling perfusion imaging
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ID: 128727
2015
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Abstract
To determine how different methods of normalizing for global cerebral blood flow (gCBF) affect image quality and sensitivity to cortical activation, pulsed arterial spin labeling (pASL) scans obtained during a visual task were normalized by either additive or multiplicative normalization of modal gCBF. Normalization by either method increased the statistical significance of cortical activation by a visual stimulus. However, image quality was superior with additive normalization, whether judged by intensity histograms or by reduced variability within gray and white matter.
| Reference Key |
stewart2015peerjadditive
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|---|---|
| Authors | ;Stephanie B. Stewart;Jonathan M. Koller;Meghan C. Campbell;Joel S. Perlmutter;Kevin J. Black |
| Journal | pediatrics |
| Year | 2015 |
| DOI |
10.7717/peerj.834
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| URL | |
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