the effects of probiotic soymilk fortified with omega-3 on blood glucose, lipid profile, haematological and oxidative stress, and inflammatory parameters in streptozotocin nicotinamide-induced diabetic rats
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2015
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Abstract
Objective. The aim of the present study was to evaluate the effects of probiotic soymilk fortified with omega-3 in diabetic rats. Methods. Soymilk (SM), fermented soymilk (FSM), and fermented soymilk fortified with omega-3 (FSM + omega-3) were prepared. Rats were randomly assigned to five groups of 13 animals per group. Diabetes was induced by a single injection of streptozotocin (STZ) 15 min after the intraperitoneal administration of nicotinamide (NA). Normal control (NC) and diabetic control (DC) rats received 1 mL/day of distilled water and three groups of diabetic rats were given 1 mL/day of SM, FSM, and FSM + omega-3 products by oral gavage for 28 days. Results. Three products significantly (P<0.05) reduced blood glucose, total cholesterol (TC), triglyceride (TG), and malondialdehyde (MDA) concentrations compared to the DC group, with the maximum reduction seen in the FSM + omega-3 group. Body weight, red blood cells (RBC), haemoglobin (Hb), haematocrit, and superoxide dismutase (SOD) also significantly increased in the FSM + omega-3 group. In the FSM + omega-3 group, MDA level compared with the SM and FSM groups and high sensitivity C-reactive protein (hs-CRP) concentrations compared with the DC and FSM groups were significantly lower (P<0.05). Conclusion. Fermented soymilk fortified with omega-3 may be beneficial in diabetes.
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| Reference Key |
sartang2015journalthe
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|---|---|
| Authors | ;Mohsen Mohammadi Sartang;Seyed Mohammad Mazloomi;Nader Tanideh;Abbas Rezaian Zadeh |
| Journal | applied computer science |
| Year | 2015 |
| DOI |
10.1155/2015/696372
|
| URL | |
| Keywords | Keywords not found |
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