Synthesis, Characterization, and Antimicrobial Activity of Novel Sulfonated Copper-Triazine Complexes

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ID: 12180
2018
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Abstract
Metallotriazine complexes possess interesting biological and medicinal properties, and the present study focuses on the synthesis, characterization, and antimicrobial activity of four novel copper-triazine derivatives in search of potent antibacterial and antifungal drug leads. In this study, 3-(2-pyridyl)-5,6-diphenyl-1,2,4-triazine-4,4′-disulfonic acid monosodium salt (L1, ferrozine) and 3-(2-pyridyl)-5,6-di(2-furyl)-1,2,4-triazine-5,5′-disulfonic acid disodium salt (L2, ferene) have been used as ligands to study the complexation towards copper(II). The synthesized complexes, [CuCl2(ferrozine)]·7H2O·MeOH (1), [CuCl2(ferrozine)2]·5H2O·MeOH (2), [CuCl2(ferene)]·H2O·MeOH (3), and [CuCl2(ferene)2]·H2O·MeOH (4), have been characterized spectroscopically, and preliminary bioassays have been carried out. FTIR spectroscopic data have shown that
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supun2018synthesisbioinorganic Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Katugampala, Supun;Perera, Inoka C.;Nanayakkara, Chandrika;Perera, Theshini;Katugampala, Supun;Perera, Inoka C.;Nanayakkara, Chandrika;Perera, Theshini;
Journal bioinorganic chemistry and applications
Year 2018
DOI
10.1155/2018/2530851
URL
https://www.hindawi.com/journals/bca/2018/2530851/abs/
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