Cytotoxic and Bactericidal Effect of Silver Nanoparticles Obtained by Green Synthesis Method Using Annona muricata Aqueous Extract and Functionalized with 5-Fluorouracil

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ID: 12174
2018
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Abstract
Nanomaterials obtained by green synthesis technologies have been widely studied in recent years owing to constitute cost-effective and environmental-friendly methods. In addition, there are several works that report the simultaneous performance of the reducer agent as a functionalizing agent, modifying the properties of the nanomaterial. As a simple and economical synthesis methodology, this work presents a method to synthesize silver nanoparticles (AgNPs) using Annona muricata aqueous extract and functionalized with 5-fluorouracil (5-FU). The processes of reduction, nucleation, and functionalization of the nanoparticles were analyzed by UV-Vis absorption spectroscopy, and it was found that they are the function of the contact time of the metal ions with the extract. The structural characterization was carried out by transmission electron microscopy (TEM) and X-ray diffraction patterns (XRD). The antibacterial properties of the synthetized nanomaterials were tested using minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against Enterococcus faecalis, Staphylococcus aureus, and Escherichia coli growth.
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carmen2018cytotoxicbioinorganic Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Sánchez-Navarro, María del Carmen;Ruiz-Torres, Claudio Adrian;Niño-Martínez, Nereyda;Sánchez-Sánchez, Roberto;Martínez-Castañón, Gabriel Alejandro;DeAlba-Montero, I.;Ruiz, Facundo;Sánchez-Navarro, María del Carmen;Ruiz-Torres, Claudio Adrian;Niño-Martínez, Nereyda;Sánchez-Sánchez, Roberto;Martínez-Castañón, Gabriel Alejandro;DeAlba-Montero, I.;Ruiz, Facundo;
Journal bioinorganic chemistry and applications
Year 2018
DOI
10.1155/2018/6506381
URL
https://www.hindawi.com/journals/bca/2018/6506381/abs/
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