Cytotoxic and Anti-Inflammatory Effects of Ent-Kaurane Derivatives Isolated from the Alpine Plant Sideritis hyssopifolia

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ID: 120600
2020
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Abstract
This paper reports the isolation and structural characterization of four new ent-kaurane derivatives from the Lamiaceae plant Sideritis hyssopifolia. Planar structures and relative configurations were determined using both mass spectrometry and nuclear magnetic resonance (1D and 2D). Absolute configurations were determined by comparing experimental and theoretical electronic circular dichroism spectra. The cytotoxic and microbial activities of all new compounds were tested. Compounds that were non-cytotoxic were further evaluated for anti-inflammatory activity.
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genta-jouve2020moleculescytotoxic Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Axelle Aimond,Kevin Calabro,Coralie Audoin,Elodie Olivier,Me´lody Dutot,Pauline Buron,Patrice Rat,Olivier Laprévote,Soizic Prado,Emmanuel Roulland,Olivier P. Thomas,Gregory Genta-Jouve;Axelle Aimond;Kevin Calabro;Coralie Audoin;Elodie Olivier;Me´lody Dutot;Pauline Buron;Patrice Rat;Olivier Laprévote;Soizic Prado;Emmanuel Roulland;Olivier P. Thomas;Gregory Genta-Jouve;
Journal molecules
Year 2020
DOI
10.3390/molecules25030589
URL
https://sciprofiles.com/publication/view/94aec3b0f066c1eab2994c095fef0bdb
Keywords
NMR anti-inflammatory sideritis hyssopifolia ent-kaurane

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