Chemical Constituents of Cymbocarpum erythraeum (DC.) Boiss., and Evaluation of Its Anti-Helicobacter pylori Activity

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ID: 12024
2018
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Abstract
Objective: Cymbocarpum erythraeum (Apiaceae) is an endemic species in Iran. Up to now, there have been no phytochemical and biological investigations on this species. Therefore, isolation of the main secondary metabolites of the plant along with its anti-H. pylori activity have been considered in this paper. Materials and Methods: The dried parts of the plant were extracted with different solvents using solvent percolation and the antibacterial activity of the extracts evaluated by the disk diffusion method. Four compounds were isolated using different column chromatography methods. Results: The compounds were identified by proton nuclear magnetic resonance and carbon-13 nuclear magnetic resonance as isoquercetin (1), rutin (2), β-sitosterol (3) and 2-decenol (4). Conclusion: Anti-H. pylori evaluation of the extracts and isolated compounds against three clinical isolates of H. pylori revealed that hexane extract of the plant inhibited all H. pylori strains.
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heidari2018chemicalturkish Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors HEIDARI, Samaneh;MANAYI, Azadeh;SAEIDNIA, Soodabeh;MIGHANI, Hossein;ESFAHANI, Hamid Reza MONSEF;GOHARI, Ahmad Reza;SETZER, William N;
Journal Turkish journal of pharmaceutical sciences
Year 2018
DOI
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URL
http://www.turkjps.org/archives/archive-detail/article-preview/chemical-constituents-of-icymbocarpum-erythraeum-i/16965
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