Lung Cancer Mortality in Tuscany from 1971 to 2010 and Its Connections with Silicosis: A Space-Cohort Analysis Based on Shared Models

Clicks: 339
ID: 11965
2018
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Ranked #10 of 44 articles by views in computational and mathematical methods in medicine

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Abstract
Lung cancer mortality in Tuscany (Italy) for males, from 1971 and 2010, is investigated. A hierarchical Bayesian model for space-time disease mapping is introduced. Such a model belongs to the class of shared random effect models and exploits the birth-cohort as the relevant time dimension. It allows for highlighting common and specific patterns of risk for each birth-cohort. The results show that different birth-cohorts exhibit quite different spatial patterns, even if the socioeconomic status is taken into account. In fact, there were different occupational exposures before and after the Second World War. The birth-cohort 1930–35 exhibits high relative risks related to particular areas. This fact could be connected with occupational exposure to risk factors for silicosis, perhaps a prognostic status for lung cancer.
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dreassi2018lungcomputational Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Dreassi, Emanuela;
Journal computational and mathematical methods in medicine
Year 2018
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