Focal nodular hyperplasia of the liver: serial MRI with Gd-DOTA, superparamagnetic iron oxide, and Gd-EOB-DTPA

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ID: 119309
2014
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Abstract
Background: To demonstrate the improved specificity of liver MRI in diagnosis of focal nodular hyperplasia (FNH) using liver specific contrast agents. Methods: In a patient after resected adenosarcoma of the uterus a focal nodular hyperplasia was followed. Serial MRI of the liver was performed using first Gd-DOTA, followed by superparamagnetic iron oxide (SPIO) as well as Gd-EOB-DTPA. Results: During the follow-up of FNH specificity of liver MRI improved using liver specific contrast agents. The central scar as well as the pseudocapsule showed different typical contrast uptake using all three methods. Conclusion: Serial MRI of the liver with Gd-DOTA, SPIO and Gd-EOB-DTPA can exclude a malignant liver lesion. Liver biopsy of FNH can be avoided with increased specificity of MRI for FNH.
Reference Key
kacl2014abdominalfocal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors G. M. Kacl;K. D. Hagspiel;B. Marincek;G. M. Kacl;K. D. Hagspiel;B. Marincek;
Journal abdominal imaging
Year 2014
DOI
doi:10.1007/s002619900186
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