Effect of combination antiretroviral therapy upon rectal mucosal HIV RNA burden and mononuclear cell apoptosis

Clicks: 417
ID: 119181
1998
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Abstract
Peripheral blood and mucosal compartments are equally responsive to effective antiretroviral therapies. The detection of significant changes within 7 days of starting antiviral therapy implies that intestinal dysfunction may be a direct result of local HIV infection.
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Authors Kotler DP;Shimada T;Snow G;Winson G;Chen W;Zhao M;Inada Y;Clayton F;;
Journal aids (london, england)
Year 1998
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/9583599
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE RNA humans pubmed abstract nih national institutes of health national library of medicine research support u.s. gov't non-p.h.s. female male Prospective Studies P.H.S. Clinical Trial intestinal mucosa / immunology viral / analysis* viral / blood drug therapy combination cd4 lymphocyte count hiv core protein p24 / blood viral load hiv infections / drug therapy* cd8-positive t-lymphocytes / immunology d p kotler cd4-positive t-lymphocytes / immunology f clayton lymphocytes / immunology* pmid:9583599 doi:10.1097/00002030-199806000-00008 t shimada anti-hiv agents / administration & dosage* apoptosis / immunology colic / drug therapy gastrointestinal diseases / drug therapy hiv core protein p24 / analysis hiv infections / physiopathology intestinal mucosa / physiopathology intestinal mucosa / virology*

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