Clinical efficacy of high-dose acyclovir in patients with human immunodeficiency virus infection: a meta-analysis of randomized individual patient data

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ID: 119097
1998
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Abstract
A meta-analysis of 8 randomized trials (1792 patients, 2947 patient-years of follow-up) showed that acyclovir (> or = 3200 mg/day) offered a significant survival benefit (P = .006 by log-rank test) in human immunodeficiency virus (HIV) infection. The treatment effect did not vary significantly in …
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Authors Ioannidis JP;Collier AC;Cooper DA;Corey L;Fiddian AP;Gazzard BG;Griffiths PD;Contopoulos-Ioannidis DG;Lau J;Pavia AT;Saag MS;Spruance SL;Youle MS;;
Journal The Journal of infectious diseases
Year 1998
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/9697714
Keywords
meta-analysis National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't adult female male P.H.S. follow-up studies dose-response relationship drug anti-hiv agents / therapeutic use* hiv infections / drug therapy* acyclovir / therapeutic use* randomized controlled trials as topic* pmid:9697714 doi:10.1086/515621 j p ioannidis a c collier m s youle

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