Eosinophil degranulation in the respiratory tract during naturally acquired respiratory syncytial virus infection

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ID: 118810
1992
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Abstract
Eosinophil cationic protein (ECP), a cytotoxic protein contained in the granules of eosinophils, has been suggested as having an important role in the pathogenesis of asthma. To determine whether ECP plays a similar role in bronchiolitis, we tested samples of nasopharyngeal secretions, obtained from …
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Authors Garofalo R;Kimpen JL;Welliver RC;Ogra PL;;
Journal the journal of pediatrics
Year 1992
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/1731020
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't Child Infant P.H.S. preschool bronchiolitis / physiopathology respirovirus infections / physiopathology pneumonia viral / blood respirovirus infections / blood probability j l kimpen r garofalo p l ogra eosinophils / physiology* respiratory syncytial viruses* respiratory tract infections / physiopathology eosinophil granule proteins ribonucleases* viral / physiopathology nasopharynx / metabolism oxygen / blood partial pressure bronchiolitis / blood respiratory tract infections / metabolism* bacterial infections / physiopathology respiratory tract infections / blood pmid:1731020 doi:10.1016/s0022-3476(05)80592-x bacterial infections / metabolism blood proteins / analysis blood proteins / pharmacokinetics* bronchiolitis / metabolism cell degranulation* / physiology eosinophils / metabolism hypoxia / blood pneumonia / metabolism pneumonia / physiopathology viral / metabolism respirovirus infections / metabolism*

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