Functions of PIWI proteins in spermatogenesis

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ID: 118412
2011
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Abstract
Recently, a significant understanding of the molecular mechanisms regulating spermatogenesis has been achieved utilizing small RNA molecules (small RNAs), including small interfering RNAs (siRNAs), microRNAs (miRNAs), and Piwi-interacting RNAs (piRNAs) which emerged as important regulators of gene expression at the post-transcriptional or translation level. piRNAs are only present in pachytene spermatocytes and round spermatids, whereas miRNAs are expressed abundantly in male germ cells throughout spermatogenesis. This review is aimed at providing a glimpse of piRNAs and their interacting family proteins such as PIWIL1, PIWIL2, and PIWIL4 in spermatogenesis.
Reference Key
choi2011clinicalfunctions Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Chong Won Bak,Tae-Ki Yoon,Youngsok Choi;Chong Won Bak;Tae-Ki Yoon;Youngsok Choi;
Journal clinical and experimental reproductive medicine
Year 2011
DOI
10.5653/cerm.2011.38.2.61
URL
https://sciprofiles.com/publication/view/e9ffe3e487317bee2b9f1baf69c2615d
Keywords
spermatogenesis infertility human mice pirnas piwi protein

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