Severe COVID-19 in the young and healthy: monogenic inborn errors of immunity?

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ID: 118409
2020
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Abstract
Severe COVID-19 is rare in previously healthy individuals who are less than 50 years of age, affecting probably no more than 1 in 1,000 such infected individuals. We suggest that these patients may become critically ill because of monogenic inborn errors that disrupt protective immunity to SARS-CoV- …
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Authors Zhang SY;Zhang Q;Casanova JL;Su HC; ;;
Journal nature reviews immunology
Year 2020
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