Androgens inhibit adipogenesis during human adipose stem cell commitment to preadipocyte formation

Clicks: 377
ID: 118093
2013
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Abstract
Androgens play a pivotal role in the regulation of body fat distribution. Adipogenesis is a process whereby multipotent adipose stem cells (ASCs) initially become preadipocytes (ASC commitment to preadipocytes) before differentiating into adipocytes. Androgens inhibit human (h) subcutaneous (SC) abd …
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Authors Chazenbalk G;Singh P;Irge D;Shah A;Abbott DH;Dumesic DA;;
Journal steroids
Year 2013
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/23707571
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE gene expression humans pubmed abstract nih national institutes of health national library of medicine research support female N.I.H. daniel a dumesic Cells Cultured Receptors androgen antagonists / pharmacology flutamide / pharmacology Lipid Metabolism adipocytes / metabolism* signal transduction ppar gamma / genetics intramural dihydrotestosterone / pharmacology* pmid:23707571 pmc3951890 doi:10.1016/j.steroids.2013.05.001 gregorio chazenbalk prapti singh adipogenesis* adult stem cells / physiology* androgens / pharmacology androgens / physiology* bone morphogenetic protein 4 / metabolism ccaat-enhancer-binding protein-beta / genetics ccaat-enhancer-binding protein-beta / metabolism ccaat-enhancer-binding proteins / genetics ccaat-enhancer-binding proteins / metabolism ppar gamma / metabolism androgen / metabolism testosterone / pharmacology testosterone / physiology*

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