Prolactin has a pathogenic role in systemic lupus erythematosus

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ID: 116195
2017
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Abstract
Prolactin, a 23-kDa peptide hormone, is produced by the anterior pituitary gland and extrapituitary sites including the immune cells. Prolactin (PRL) participates in innate and adaptive immune response. PRL stimulates the immune cells by binding to receptor (PRL-R). Binding of PRL to its receptor ac …
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Authors Jara LJ;Medina G;Saavedra MA;Vera-Lastra O;Torres-Aguilar H;Navarro C;Vazquez Del Mercado M;Espinoza LR;;
Journal immunologic research
Year 2017
DOI
DOI not found
URL
https://www.pubmed.gov/28130617/
Keywords
immunity National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals humans pubmed abstract nih national institutes of health national library of medicine pregnancy female Disease Models Animal Hyperprolactinemia / epidemiology Lupus Erythematosus Systemic / epidemiology Antibodies Receptors pregnancy complications / epidemiology pregnancy complications / immunology* innate immunocompetence prolactin / metabolism* pmid:28130617 doi:10.1007/s12026-016-8891-x luis j jara gabriela medina luis r espinoza adaptive immunity antinuclear / blood bromocriptine / therapeutic use* dopamine agonists / therapeutic use* hyperprolactinemia / drug therapy hyperprolactinemia / immunology* systemic / drug therapy systemic / immunology* lupus nephritis / drug therapy lupus nephritis / immunology* pregnancy complications / drug therapy prolactin / immunology prolactin / metabolism

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