The antiviral activity of SP-303, a natural polyphenolic polymer, against respiratory syncytial and parainfluenza type 3 viruses in cotton rats

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ID: 116162
1993
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Abstract
SP-303, a naturally occurring polyphenolic polymer (average M.W. = 2100 Da), was tested in cotton rats (Sigmoden hispidus) for antiviral activity against respiratory syncytial (RSV) and parainfluenza type 3 (PIV3) viruses, and for acute toxicity. Significant reductions in pulmonary RSV titers, compa …
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Authors Wyde PR;Ambrose MW;Meyerson LR;Gilbert BE;;
Journal Antiviral research
Year 1993
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/8384824
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE animals pubmed abstract nih national institutes of health national library of medicine research support u.s. gov't P.H.S. Body Weight p r wyde lung / pathology sigmodontinae lung / microbiology respirovirus infections / prevention & control* antiviral agents / administration & dosage antiviral agents / therapeutic use* respiratory syncytial viruses / drug effects* human / drug effects* respirovirus infections / microbiology culture techniques viral plaque assay pmid:8384824 doi:10.1016/0166-3542(93)90004-3 m w ambrose b e gilbert biopolymers / pharmacology* catechin / analogs & derivatives* catechin / pharmacology parainfluenza virus 3 paramyxoviridae infections / microbiology paramyxoviridae infections / prevention & control* plants medicinal / chemistry ribavirin / pharmacology

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