Adipose tissue expandability and the early origins of PCOS

Clicks: 285
ID: 115809
2009
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Abstract
The most prevalent phenotypes of polycystic ovary syndrome (PCOS) are characterized by insulin resistance and androgen excess. The adipose tissue (AT) expandability hypothesis explains the development of insulin resistance in obesity and in cases of AT deficit. In line with this hypothesis, we propo …
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Authors de Zegher F;Lopez-Bermejo A;Ibáñez L;;
Journal trends in endocrinology and metabolism: tem
Year 2009
DOI
DOI not found
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http://www.ncbi.nlm.nih.gov/pubmed/19796964
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE review animals humans pubmed abstract nih national institutes of health national library of medicine pregnancy research support non-u.s. gov't female male Adipose Tissue / metabolism* polycystic ovary syndrome / metabolism polycystic ovary syndrome / etiology* adipose tissue / pathology* androgens / physiology insulin resistance / physiology pmid:19796964 doi:10.1016/j.tem.2009.06.003 francis de zegher abel lopez-bermejo lourdes ibáñez androgens / metabolism hyperinsulinism / metabolism hyperinsulinism / physiopathology polycystic ovary syndrome / pathology

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