C/EBPalpha is required for differentiation of white, but not brown, adipose tissue

Clicks: 283
ID: 115511
2001
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Abstract
The transcription factor CCAAT enhancer binding protein alpha (C/EBPalpha) is expressed at high levels in liver and adipose tissue. Cell culture studies show that C/EBPalpha is sufficient to trigger differentiation of preadipocytes into mature adipocytes, suggesting a central role for C/EBPalpha in …
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Authors Linhart HG;Ishimura-Oka K;DeMayo F;Kibe T;Repka D;Poindexter B;Bick RJ;Darlington GJ;;
Journal Proceedings of the National Academy of Sciences of the United States of America
Year 2001
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/11606718
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't P.H.S. Adipose Tissue / cytology* adipose tissue cell differentiation liver / metabolism transgenic pmid:11606718 pmc60088 doi:10.1073/pnas.211416898 h g linhart k ishimura-oka g j darlington brown / cytology* ccaat-enhancer-binding protein-alpha / physiology* fatty liver / etiology hyperlipidemias / etiology lipoprotein lipase / genetics

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