Irritability and Its Clinical Utility in Major Depressive Disorder: Prediction of Individual-Level Acute-Phase Outcomes Using Early Changes in Irritability and Depression Severity

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ID: 115448
2019
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Abstract
Irritability is an important symptom domain of major depressive disorder that is not fully reflected in depressive symptom severity measures. Early reductions in irritability, when combined with changes in depressive symptom severity, provide a robust estimate of likelihood of remission or no meanin …
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Authors Jha MK;Minhajuddin A;South C;Rush AJ;Trivedi MH;;
Journal the american journal of psychiatry
Year 2019
DOI
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URL
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=30922100&dopt=Abstract
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine logistic models prognosis treatment outcome research support non-u.s. gov't adult female male N.I.H. Extramural Depressive Disorder Major / psychology middle aged randomized controlled trials as topic severity of illness index antidepressive agents / therapeutic use* single-blind method pmid:30922100 doi:10.1176/appi.ajp.2018.18030355 manish k jha abu minhajuddin madhukar h trivedi ambulatory care bupropion / therapeutic use citalopram / therapeutic use major / drug therapy* irritable mood* mirtazapine / therapeutic use venlafaxine hydrochloride / therapeutic use

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