Cytotoxic T cells clear virus but augment lung pathology in mice infected with respiratory syncytial virus

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ID: 115312
1988
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Abstract
We have examined the function of class I MHC-restricted cytotoxic T cells in experimental respiratory syncytial virus (RSV) infection of BALB/c mice by transfer of T cell line MJC-A2 and CTL clone E8a into RSV-infected mice. The T cell line cleared pulmonary RSV infection within 5 d in persistently …
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Authors Cannon MJ;Openshaw PJ;Askonas BA;;
Journal The Journal of experimental medicine
Year 1988
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/3262705
Keywords
immunization National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals pubmed abstract nih national institutes of health national library of medicine Inbred BALB C passive lung / microbiology respiratory syncytial viruses / immunology t-lymphocytes lung / immunology respirovirus infections / immunology* cytotoxic / immunology* p j openshaw respirovirus infections / pathology respirovirus infections / microbiology pmid:3262705 pmc2189034 doi:10.1084/jem.168.3.1163 m j cannon b a askonas clone cells dimercaprol lung / pathology*

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