Cytotoxic T cells clear virus but augment lung pathology in mice infected with respiratory syncytial virus

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ID: 115312
1988
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Abstract
We have examined the function of class I MHC-restricted cytotoxic T cells in experimental respiratory syncytial virus (RSV) infection of BALB/c mice by transfer of T cell line MJC-A2 and CTL clone E8a into RSV-infected mice. The T cell line cleared pulmonary RSV infection within 5 d in persistently …
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Authors Cannon MJ;Openshaw PJ;Askonas BA;;
Journal The Journal of experimental medicine
Year 1988
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