Potent inhibition of respiratory syncytial virus by polyoxometalates of several structural classes

Clicks: 359
ID: 114749
1997
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Abstract
A series of polyoxometalates (POM) were synthesized and evaluated for anti-respiratory syncytial virus (RSV) activity. POM containing zirconium, tungsten, silicon, platinum, niobium or germanium of a variety of structural types have been evaluated. Sixteen of the compounds had very striking anti-RSV …
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Authors Barnard DL;Hill CL;Gage T;Matheson JE;Huffman JH;Sidwell RW;Otto MI;Schinazi RF;;
Journal Antiviral research
Year 1997
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/9107383
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE animals humans pubmed abstract nih national institutes of health national library of medicine research support u.s. gov't non-p.h.s. P.H.S. Cultured cell line cattle respiratory syncytial viruses / drug effects* antiviral agents / pharmacology* respiratory syncytial viruses / physiology cell survival / drug effects tumor cells pmid:9107383 doi:10.1016/s0166-3542(96)01019-4 d l barnard c l hill r f schinazi cytopathogenic effect viral / drug effects respiratory syncytial viruses / pathogenicity virus replication / drug effects

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