Tumor induction of VEGF promoter activity in stromal cells

Clicks: 436
ID: 114372
1998
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Abstract
We have established a line of transgenic mice expressing the A. victoria green fluorescent protein (GFP) under the control of the promoter for vascular endothelial growth factor (VEGF). Mice bearing the transgene show green cellular fluorescence around the healing margins and throughout the granulat …
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Authors Fukumura D;Xavier R;Sugiura T;Chen Y;Park EC;Lu N;Selig M;Nielsen G;Taksir T;Jain RK;Seed B;;
Journal Cell
Year 1998
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/9753319
Keywords
experimental National Center for Biotechnology Information NCBI NLM MEDLINE Mice gene expression regulation animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't female male P.H.S. Cell Division / physiology Cells Cultured Genes b seed neoplastic* Promoter Regions microscopy electron green fluorescent proteins luminescent proteins / genetics transgenic indicators and reagents tumor cells pmid:9753319 doi:10.1016/s0092-8674(00)81731-6 d fukumura r xavier endothelial growth factors / genetics* fibroblasts / cytology fibroblasts / physiology fibroblasts / ultrastructure reporter lymphokines / genetics* mammary neoplasms genetic / genetics* skin / injuries stromal cells / physiology* stromal cells / ultrastructure cultured / cytology cultured / physiology vascular endothelial growth factor a vascular endothelial growth factors wound healing / genetics

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