Androgen signaling pathways driving reproductive and metabolic phenotypes in a PCOS mouse model

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2020
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Abstract
As the mechanistic basis of polycystic ovary syndrome (PCOS) remains unknown, current management relies on symptomatic treatment. Hyperandrogenism is a major PCOS characteristic and evidence supports it playing a key role in PCOS pathogenesis. Classically, androgens can act directly through the andr …
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Authors Aflatounian A;Edwards MC;Rodriguez Paris V;Bertoldo MJ;Desai R;Gilchrist RB;Ledger WL;Handelsman DJ;Walters KA;;
Journal the journal of endocrinology
Year 2020
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