Protein binding and its significance in antibacterial therapy

Clicks: 369
ID: 113215
1989
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Abstract
Serum protein binding of antimicrobials can reduce antimicrobial activity, restrict tissue distribution, and delay drug elimination. Binding percentages of 80 per cent or more have the potential to significantly reduce free drug levels and affect therapeutic efficacy in patients. However, binding-in …
Reference Key
wa1989infectiousprotein Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Craig WA;Ebert SC;;
Journal infectious disease clinics of north america
Year 1989
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/2671130
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE review humans pubmed abstract nih national institutes of health national library of medicine anti-bacterial agents / therapeutic use pmid:2671130 w a craig s c ebert anti-bacterial agents / pharmacokinetics* blood proteins / metabolism* protein binding

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