Associations of Suboptimal Growth with All-Cause and Cause-Specific Mortality in Children under Five Years: A Pooled Analysis of Ten Prospective Studies

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ID: 112818
2013
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Abstract
Background Child undernutrition affects millions of children globally. We investigated associations between suboptimal growth and mortality by pooling large studies. Methods Pooled analysis involving children 1 week to 59 months old in 10 prospective studies in Africa, Asia and South America. Utilizing most recent measurements, we calculated weight-for-age, height/length-for-age and weight-for-height/length Z scores, applying 2006 WHO Standards and the 1977 NCHS/WHO Reference. We estimated all-cause and cause-specific mortality hazard ratios (HR) using proportional hazards models comparing children with mild (−2≤Z
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Authors Ibironke Olofin;Christine M. McDonald;Majid Ezzati;Seth Flaxman;Robert E. Black;Wafaie W. Fawzi;Laura E. Caulfield;Goodarz Danaei;for the Nutrition Impact Model Study (anthropometry cohort pooling);
Journal PloS one
Year 2013
DOI
10.1371/journal.pone.0064636
URL
https://dx.doi.org/10.1371%2Fjournal.pone.0064636
Keywords
Children nutrition child health respiratory infections malnutrition malaria anthropometry Death rates National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't female male Child Infant Prospective Studies newborn preschool growth disorders / epidemiology risk factors anthropometry Growth Disorders / complications Proportional Hazards Models body weight / physiology asia / epidemiology body height / physiology south america / epidemiology risk assessment / methods growth disorders / physiopathology* christine m mcdonald pmid:23734210 pmc3667136 doi:10.1371/journal.pone.0064636 ibironke olofin nutrition impact model study (anthropometry cohort pooling) africa / epidemiology cause of death* mortality / trends* risk assessment / statistics & numerical data thinness / complications thinness / epidemiology thinness / physiopathology*

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