The factors present in regenerating muscles impact bone marrow-derived mesenchymal stromal/stem cell fusion with myoblasts

再生肌肉中存在的因子影响骨髓来源间充质基质/干细胞与成肌细胞的融合

Clicks: 537
ID: 112575
2019
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Abstract
To conclude, our study revealed that treatment with IGF-1, IL-4, IL-6, or SDF-1 affects BM-MSC interaction with myoblasts; however, it does not directly promote myogenic differentiation of these cells.
综上所述，本研究表明，IGF-1、IL-4、IL-6 或 SDF-1 处理会影响 BM-MSC 与成肌细胞的相互作用；然而，这并不能直接促进这些细胞的肌源性分化。
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Authors Kasprzycka P;Archacka K;Kowalski K;Mierzejewski B;Zimowska M;Grabowska I;Piotrowski M;Rafałko M;Ryżko A;Irhashava A;Senderowski K;Gołąbek M;Stremińska W;Jańczyk-Ilach K;Koblowska M;Iwanicka-Nowicka R;Fogtman A;Janowski M;Walczak P;Ciemerych MA;Brzoska E;;
Journal stem cell research & therapy
Year 2019
DOI
DOI not found
URL
https://www.pubmed.gov/31753006/
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE animals humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't cell line mesenchymal stem cells / cytology mesenchymal stem cells / metabolism* muscle fibers skeletal / physiology* pmid:31753006 pmc6873517 doi:10.1186/s13287-019-1444-1 paulina kasprzycka karolina archacka edyta brzoska bone marrow cells / cytology bone marrow cells / metabolism* cell fusion skeletal / cytology myoblasts / cytology myoblasts / metabolism* regeneration* swine

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