UPARANT is an effective antiangiogenic agent in a mouse model of rubeosis iridis
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ID: 112407
2019
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Abstract
Puncture-induced iris neovascularization (rubeosis iridis; RI) in mice is associated with upregulation of extracellular matrix (ECM) degradation and inflammatory factors. The anti-angiogenic and anti-inflammatory efficacy of UPARANT in reducing RI was determined by noninvasive, in vivo iris vascular …
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| Reference Key |
f2019journaluparant
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|---|---|
| Authors | Locri F;Dal Monte M;Aronsson M;Cammalleri M;De Rosa M;Pavone V;Kvanta A;Bagnoli P;André H;; |
| Journal | journal of molecular medicine (berlin, germany) |
| Year | 2019 |
| DOI |
DOI not found
|
| URL | |
| Keywords |
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
female
male
Disease Models
Animal
Inbred BALB C
pmid:31243519
pmc6713680
doi:10.1007/s00109-019-01794-w
filippo locri
massimo dal monte
helder andré
angiogenesis inhibitors / pharmacology*
biomarkers / metabolism
inflammation / drug therapy
inflammation / metabolism
iris / drug effects*
iris / metabolism
neovascularization
pathologic / drug therapy*
pathologic / metabolism
vascular endothelial growth factor a / metabolism
|
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