UPARANT is an effective antiangiogenic agent in a mouse model of rubeosis iridis

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ID: 112407
2019
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Abstract
Puncture-induced iris neovascularization (rubeosis iridis; RI) in mice is associated with upregulation of extracellular matrix (ECM) degradation and inflammatory factors. The anti-angiogenic and anti-inflammatory efficacy of UPARANT in reducing RI was determined by noninvasive, in vivo iris vascular …
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Authors Locri F;Dal Monte M;Aronsson M;Cammalleri M;De Rosa M;Pavone V;Kvanta A;Bagnoli P;André H;;
Journal journal of molecular medicine (berlin, germany)
Year 2019
DOI
DOI not found
URL
https://www.pubmed.gov/31243519/
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't female male Disease Models Animal Inbred BALB C pmid:31243519 pmc6713680 doi:10.1007/s00109-019-01794-w filippo locri massimo dal monte helder andré angiogenesis inhibitors / pharmacology* biomarkers / metabolism inflammation / drug therapy inflammation / metabolism iris / drug effects* iris / metabolism neovascularization pathologic / drug therapy* pathologic / metabolism vascular endothelial growth factor a / metabolism

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