Autophagy promotes fibrosis and apoptosis in the peritoneum during long-term peritoneal dialysis

Clicks: 323
ID: 112230
2018
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Abstract
Long-term peritoneal dialysis is accompanied by functional and histopathological alterations in the peritoneal membrane. In the long process of peritoneal dialysis, high-glucose peritoneal dialysis solution (HGPDS) will aggravate the peritoneal fibrosis, leading to decreased effectiveness of periton …
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Authors Wu J;Xing C;Zhang L;Mao H;Chen X;Liang M;Wang F;Ren H;Cui H;Jiang A;Wang Z;Zou M;Ji Y;;
Journal Journal of cellular and molecular medicine
Year 2018
DOI
DOI not found
URL
https://www.pubmed.gov/29077259/
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't adult male middle aged signal transduction / drug effects epithelium / pathology catheterization pmid:29077259 pmc5783841 doi:10.1111/jcmm.13393 jingjing wu changying xing yong ji apoptosis* / drug effects autophagy* / drug effects beclin-1 / metabolism dialysis solutions / pharmacology epithelial-mesenchymal transition / drug effects epithelium / metabolism epithelium / ultrastructure glucose peritoneal dialysis / adverse effects* peritoneal fibrosis / etiology* peritoneal fibrosis / pathology* peritoneum / drug effects peritoneum / pathology* peritoneum / ultrastructure smad proteins / metabolism transforming growth factor beta1 / metabolism

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