Diagnosis of bacteremic pneumococcal pneumonia by amplification of pneumolysin gene fragment in serum

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ID: 112139
1995
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Abstract
A polymerase chain reaction (PCR) assay based on the amplification of pneumolysin gene fragments in patient sera was developed for the etiologic diagnosis of acute pneumococcal pneumonia. Two pairs of oligonucleotide primers were designed to amplify a 348-bp and a 208-bp fragment of the pneumolysin …
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Authors Salo P;Ortqvist A;Leinonen M;;
Journal The Journal of infectious diseases
Year 1995
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/7844395
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't adult aged Genes sensitivity and specificity Polymerase Chain Reaction / methods* bacterial* pneumonia pneumococcal / diagnosis* streptococcus pneumoniae / genetics bacteremia / diagnosis* bacterial proteins pmid:7844395 doi:10.1093/infdis/171.2.479 p salo a ortqvist m leinonen streptolysins / genetics*

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