Native human antibody to Shr promote mice survival after intraperitoneal challenge with invasive Group A Streptococcus.

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ID: 111847
2020
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Ranked #140 of 432 articles by views in The Journal of infectious diseases

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Abstract
A vaccine against the group A streptococcus (GAS) has been actively pursued for decades. The surface receptor Shr is vital in GAS heme uptake and provides an effective target for active and passive immunization. Here, we isolated human monoclonal antibodies (mAbs) against Shr and evaluated their efficacy and mechanism.
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chatterjee2020thenative Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Nilanjana Chatterjee;Ya-Shu Huang;Kristin V Lyles;Julie E Morgan;Lawrence M Kauvar;Susanna F Greer;Zehava Eichenbaum;
Journal The Journal of infectious diseases
Year 2020
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