The pyrin inflammasome and the Yersinia effector interaction
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2020
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Abstract
Pyrin is a cytosolic pattern-recognition receptor that normally functions as a guard to trigger capase-1 inflammasome assembly in response to bacterial toxins and effectors that inactivate RhoA. The MEFV gene encoding human pyrin is preferentially expressed in phagocytes. Key domains in pyrin includ …
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| Authors | Malik HS;Bliska JB;; |
| Journal | immunological reviews |
| Year | 2020 |
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