Inflammatory and coagulation biomarkers and mortality in patients with HIV infection

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ID: 110807
2008
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Abstract
IL-6 and D-dimer were strongly related to all-cause mortality. Interrupting ART may further increase the risk of death by raising IL-6 and D-dimer levels. Therapies that reduce the inflammatory response to HIV and decrease IL-6 and D-dimer levels may warrant investigation.
Reference Key
lh2008plosinflammatory Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Kuller LH;Tracy R;Belloso W;De Wit S;Drummond F;Lane HC;Ledergerber B;Lundgren J;Neuhaus J;Nixon D;Paton NI;Neaton JD; ;;
Journal plos medicine
Year 2008
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/18942885
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine logistic models treatment outcome research support female male N.I.H. Extramural randomized controlled trials as topic follow-up studies case-control studies pmid:18942885 pmc2570418 doi:10.1371/journal.pmed.0050203 lewis h kuller russell tracy insight smart study group anti-hiv agents / therapeutic use biomarkers / blood* blood coagulation c-reactive protein / analysis cause of death fibrin fibrinogen degradation products / analysis hiv infections / blood* hiv infections / drug therapy hiv infections / mortality* inflammation / blood interleukin-6 / blood multicenter studies as topic odds ratio serum amyloid a protein / analysis serum amyloid p-component / analysis survival rate inflammation hiv biomarkers antiretroviral therapy hiv infections co-infections Death rates medical risk factors

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