Genetically determined susceptibility to mycobacterial infection

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2008
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Abstract
Individuals with impaired cell mediated immunity exhibit increased susceptibility to infections caused by poorly pathogenic mycobacteria (non-tuberculous mycobacteria and BCG), as well as salmonella species. However, these infections may also occur in a disseminated, fatal form, sometimes with a fam …
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Authors Patel SY;Doffinger R;Barcenas-Morales G;Kumararatne DS;;
Journal journal of clinical pathology
Year 2008
DOI
DOI not found
URL
https://www.ncbi.nlm.nih.gov/pubmed/18326015
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE review humans pubmed abstract nih national institutes of health national library of medicine Receptors Genotype mutation pmid:18326015 doi:10.1136/jcp.2007.051201 s y patel r doffinger d s kumararatne cytokines / immunology* genetic predisposition to disease* interferon-gamma / genetics interleukin-12 / deficiency interleukin-12 / immunology interleukin-12 subunit p40 / deficiency interleukin-12 subunit p40 / genetics interleukin-23 / deficiency interleukin-23 / immunology mycobacterium infections nontuberculous / genetics* nontuberculous / immunology mycobacterium bovis / immunology interferon / genetics interleukin-12 / genetics stat1 transcription factor / deficiency stat1 transcription factor / genetics tyk2 kinase / genetics

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