Trial Reporting in Immuno-Oncology (TRIO): An American Society of Clinical Oncology-Society for Immunotherapy of Cancer Statement

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ID: 109361
2018
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Abstract
Abstract Purpose To develop recommendations for clinical trial reporting that address the unique efficacy, toxicity, and combination and sequencing aspects of immuno-oncology (IO) treatments. Methods ASCO and the Society for Immunotherapy of Cancer (SITC) convened a working group that consisted of practicing medical oncologists, immunologists, clinical researchers, biostatisticians, and representatives from industry and government to develop Trial Reporting in Immuno-Oncology (TRIO) recommendations. These recommendations are based on expert consensus, given that existing data to support evidence-based recommendations are limited. Conclusion The TRIO recommendations are intended to improve the reporting of IO clinical trials and thus provide more complete evidence on the relative benefits and risks of an IO therapeutic approach. Given the rapid expansion of the number of IO clinical trials and ongoing improvements to the evidence base supporting the use of IO treatments in clinical care, these recommendations will likely need regular revision as the IO field develops.
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tsimberidou2018trialjournal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Tsimberidou, Apostolia M.;Levit, Laura A.;Schilsky, Richard L.;Averbuch, Steven D.;Chen, Daniel;Kirkwood, John M.;McShane, Lisa M.;Sharon, Elad;Mileham, Kathryn F.;Postow, Michael A.;
Journal journal for immunotherapy of cancer
Year 2018
DOI
DOI not found
URL
http://link.springer.com/article/10.1186/s40425-018-0426-7
Keywords
chemistry Medicine Science Dentistry sports neoplasms. tumors. oncology. including cancer and carcinogens agriculture public aspects of medicine meteorology. climatology

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