Advances in Therapeutic Approaches for Spontaneous Intracerebral Hemorrhage.

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ID: 109323
2020
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Ranked #3 of 4 articles by views in neurotherapeutics : the journal of the american society for experimental neurotherapeutics

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Abstract
Spontaneous intracerebral hemorrhage (ICH) results in high rates of morbidity and mortality, with intraventricular hemorrhage (IVH) being associated with even worse outcomes. Therapeutic interventions in acute ICH have continued to emerge with focus on arresting hemorrhage expansion, clot volume reduction of both intraventricular and parenchymal hematomas, and targeting perihematomal edema and inflammation. Large randomized controlled trials addressing the effectiveness of rapid blood pressure lowering, hemostatic therapy with platelet transfusion, and other clotting complexes and hematoma volume reduction using minimally invasive techniques have impacted clinical guidelines. We review the recent evolution in the management of acute spontaneous ICH, discussing which interventions have been shown to be safe and which may potentially improve outcomes.
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alkawaz2020advancesneurotherapeutics Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Al-Kawaz, Mais N;Hanley, Daniel F;Ziai, Wendy;
Journal neurotherapeutics : the journal of the american society for experimental neurotherapeutics
Year 2020
DOI
10.1007/s13311-020-00902-w
URL
Keywords
stroke intraventricular hemorrhage outcomes fibrinolysis intracerebral hemorrhage

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