Kinetics of Chemical Processes in the Human Brain. The Cholinergic Synapse-Mechanisms of Functioning and Control Methods.

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ID: 108643
2020
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Abstract
In the framework of the kinetic model, the functioning of the cholinergic synapse is considered. The results of mathematical modeling of changes in the level of acetylcholine, induced pH impulse, the influence of the frequency of impulse transmission and inhibition of acetylcholinesterase are presented. Physicochemical explanation for a number of important physiological phenomena, such as neuromuscular paralysis, the molecular mechanism of neurological memory, and actions of nerve poisons and toxins, is given.
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varfolomeev2020kineticsdoklady Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Varfolomeev, S D;Bykov, V I;Tsybenova, S B;
Journal doklady biochemistry and biophysics
Year 2020
DOI
10.1134/S1607672920030126
URL
Keywords
kinetic model human brain acetylcholine botulinum toxin catalytic activity of enzyme cholinergic synapse dynamics of process frequency of impulse transmission inhibition of acetylcholinesterase neurological memory neuromuscular contraction synaptic cleft

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