A Guide to COVID-19: a global pandemic caused by the novel coronavirus SARS-CoV-2.

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ID: 106931
2020
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Abstract
The emergence of the SARS-CoV-2 strain of the human coronavirus has thrown the world into the midst of a new pandemic. In the human body, the virus causes COVID-19, a disease characterized by shortness of breath, fever, and pneumonia, which can be fatal in vulnerable individuals. SARS-CoV-2 has characteristics of past human coronaviruses, with close genomic similarities to SARS-CoV, the virus that causes the disease SARS. Like these related coronaviruses, SARS-CoV-2 is transmitted through the inhalation of droplets and interaction with contaminated surfaces. Across the world, laboratories are developing candidate vaccines for the virus - with vaccine trials underway in the US and the United Kingdom - and considering various drugs for possible treatments and prophylaxis. Here, we provide an overview of SARS-CoV-2 by analyzing its virology, epidemiology, and modes of transmission while examining the current progress of testing procedures and possible treatments through drugs and vaccines.
Reference Key
atzrodt2020athe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Atzrodt, Cassandra L;Maknojia, Insha;McCarthy, Robert D P;Oldfield, Tiara M;Po, Jonathan;Ta, Kenny T L;Stepp, Hannah E;Clements, Thomas P;
Journal The FEBS Journal
Year 2020
DOI
10.1111/febs.15375
URL
Keywords
mers mers-cov coronavirus vaccine hydroxychloroquine sars-cov crispr rt-qpcr chloroquine sars covid-19 sars-cov-2 ace2 remdesivir

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