Vascular Protective Effects of Morinda citrifolia Leaf Extract on Postmenopausal Rats Fed with Thermoxidized Palm Oil Diet: Evidence at Microscopic Level
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ID: 10664
2018
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Abstract
Atherosclerosis is now well understood as an inflammatory disease instead of lipid storage disorder; however, the conventional treatment is not targeted on treating the inflammation. Morinda citrifolia L. (Rubiaceae) leaf or noni leaf, which is a medicinal food (ulam) used in Traditional Malay Medicine to prevent chronic diseases, may have the potential to be formulated into a functional antiatherosclerotic agent. This study aimed to investigate the effectiveness of Morinda citrifolia leaf extract (MCLE) treatment at histological and ultrastructural level, comparing it with Simvastatin. Thirty-eight female Sprague Dawley rats were divided into five groups: Sham (Sham), ovariectomized (OVX), ovariectomized with Simvastatin 10 mg/kg (OVX
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| Reference Key |
g2018vascularinternational
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|---|---|
| Authors | Chong, C. L. G.;Othman, Faizah;Hussan, Farida;Chong, C. L. G.;Othman, Faizah;Hussan, Farida; |
| Journal | international journal of vascular medicine |
| Year | 2018 |
| DOI |
10.1155/2018/6317434
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| URL | |
| Keywords | Keywords not found |
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