Round Spermatid Injection.

Clicks: 343
ID: 106005
2020
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Abstract
From a fertility perspective, men with azoospermia represent a challenging patient population. When no mature spermatozoa are obtained during a testicular sperm extraction, patients are often left with limited options, such as adoption or the use of donor sperm. However, it has been reported that round spermatids can be successfully injected into human oocytes and used as an alternative to mature spermatozoa. This technique is known as round spermatid injection (ROSI). Despite the limitations of ROSI and diminished clinical success rates, the use of round spermatids for fertilization may have potential as a treatment modality for men with azoospermia.
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Authors Gross, Kelli X;Hanson, Brent M;Hotaling, James M;
Journal the urologic clinics of north america
Year 2020
DOI
S0094-0143(19)30111-9
URL
Keywords
azoospermia assisted reproductive technology in vitro fertilization male factor infertility round spermatid injection testicular sperm extraction

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