Zinc oxide nanoparticles: Biosynthesis, characterization, antifungal and cytotoxic activity.

Clicks: 326
ID: 105533
2019
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Abstract
Zinc oxide nanoparticles (ZnO-NPs) are multifunctional oxide metal nanoparticles that have been considered by many due to their unique properties including UV filtration, semiconducting, antimicrobial, antifungal, and photocatalytic activity. In the present study, ZnO-NPs have been synthesized from Zn(SO)·7HO through the use of "green synthesis" method that utilizes Prosopis farcta aqueous extract. The characterization of synthesized ZnO-NPs have been performed by UV-Vis absorption, Fourier-Transform Infrared spectroscopy (FT-IR), Raman, Powder X-ray Diffraction (PXRD), Transmission Electron Microscopy (TEM), Field Emission Scanning Electron Microscopy (FESEM) and Energy Dispersive X-ray analysis (EDX). Results have illustrated that the synthesized nanoparticles contain a hexagonal shape and sheet form with sizes of 40-80 nm. The antifungal activity of ZnO-NPs against Candida albicans has shown that the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) were 128 and 256 μg/ml, respectively. The cytotoxicity activity of synthesized nanoparticles was tested on breast cancer cells (MCF7), while the IC was calculated to be 90 μg/ml.
Reference Key
miri2019zincmaterials Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Miri, Abdolhossien;Mahdinejad, Nafiseh;Ebrahimy, Omolbanin;Khatami, Mehrdad;Sarani, Mina;
Journal materials science & engineering c, materials for biological applications
Year 2019
DOI
S0928-4931(18)31090-7
URL
Keywords
mcf7 candida albicans prosopis farcta fesem zno-nps

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