Convergent evolution of small molecule pheromones in nematodes.

Clicks: 290
ID: 105091
2020
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #31 of 128 articles by views in eLife

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 128 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
The small molecules that mediate chemical communication between nematodes-so-called 'nematode-derived-modular-metabolites' (NDMMs)-are of major interest due to their ability to regulate development, behavior, and life-history. nematodes produce an impressive diversity of structurally complex NDMMs, some of which act as primer pheromones capable of triggering irreversible developmental switches. Many of these NDMMs have only ever been found in but no attempts had been made to study their evolution by profiling closely related species. This study was designed to bring a comparative perspective to the biochemical study of NDMMs via the systematic MS/MS and NMR-based analysis of -metabolomes from over 30 species. We identified 36 novel compounds and found evidence for the convergent evolution of complex NDMMs in separate branches of the phylogeny. Our results demonstrate that biochemical innovation is a recurrent process in nematodes, a pattern likely typical across the animal kingdom.
Reference Key
dong2020convergentelife Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Dong, Chuanfu;Weadick, Cameron J;Truffault, Vincent;Sommer, Ralf J;
Journal eLife
Year 2020
DOI
10.7554/eLife.55687
URL
Keywords
evolutionary biology

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.