Exploring Seipin: From Biochemistry to Bioinformatics Predictions

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ID: 10484
2018
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Abstract
Seipin is a nonenzymatic protein encoded by the BSCL2 gene. It is involved in lipodystrophy and seipinopathy diseases. Named in 2001, all seipin functions are still far from being understood. Therefore, we reviewed much of the research, trying to find a pattern that could explain commonly observed features of seipin expression disorders. Likewise, this review shows how this protein seems to have tissue-specific functions. In an integrative view, we conclude by proposing a theoretical model to explain how seipin might be involved in the triacylglycerol synthesis pathway.
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sales2018exploringinternational Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Craveiro Sarmento, Aquiles Sales;de Azevedo Medeiros, Lázaro Batista;Agnez-Lima, Lucymara Fassarella;Lima, Josivan Gomes;de Melo Campos, Julliane Tamara Araújo;Craveiro Sarmento, Aquiles Sales;de Azevedo Medeiros, Lázaro Batista;Agnez-Lima, Lucymara Fassarella;Lima, Josivan Gomes;de Melo Campos, Julliane Tamara Araújo;
Journal international journal of cell biology
Year 2018
DOI
10.1155/2018/5207608
URL
https://www.hindawi.com/journals/ijcb/2018/5207608/abs/
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