Hydrazide-hydrazones as potential antimicrobial agents: overview of the literature since 2010.

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Abstract
Hydrazide-hydrazone derivatives are present in many bioactive molecules and display a wide variety of biological activities, such as antibacterial, antitubercular, antifungal, anticancer, anti-inflammatory, anticonvulsant, antiviral, and antiprotozoal action. Therefore, many medicinal chemists synthesize various hydrazide-hydrazones and evaluate them for biological activities. Among biological properties of this class of compounds, antimicrobial activity is the most frequently encountered in scientific literature. This paper is focused on the overview of the literature findings of the last six years (2010-2016) covering the research on antimicrobial activity of hydrazide-hydrazone derivatives. This review may also serve as a useful guide for the development of new hydrazide-hydrazones as potential antimicrobial agents.
Reference Key
popioekhydrazidehydrazonesmedicinal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Popiołek, Łukasz;
Journal medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents
Year Year not found
DOI
10.1007/s00044-016-1756-y
URL
Keywords
Antifungal Activity antibacterial activity mic antitubercular activity hydrazide–hydrazone

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