Synthesis and investigation of antimicrobial activities of nitrofurazone analogues containing hydrazide-hydrazone moiety.

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ID: 104500
2017
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Abstract
In this research we synthesized and tested for antimicrobial activity 21 nitrofurazone analogues. The compounds we obtained were identified on the basis of H NMR and C NMR spectroscopy. The screening of antimicrobial properties of synthesized compounds revealed a wide spectrum of antimicrobial activity. Compounds , , -, and - showed very high bactericidal effect towards spp. ATTC and spp. ATTC (MIC = 0.002-7.81 µg/ml and MBC = 0.002-31.25 µg/ml). The levels of activity of several compounds were far better than those of nitrofurantoin, ciprofloxacin or cefuroxime.
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popioek2017synthesissaudi Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Popiołek, Łukasz;Biernasiuk, Anna;
Journal saudi pharmaceutical journal : spj : the official publication of the saudi pharmaceutical society
Year 2017
DOI
10.1016/j.jsps.2017.05.006
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