Synthesis and Bioactivity of Hydrazide-Hydrazones with the 1-Adamantyl-Carbonyl Moiety.

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ID: 104488
2019
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Abstract
Reaction of 1-adamantyl carbohydrazide () with various substituted benzaldehydes and acetophenones yielded the corresponding hydrazide-hydrazones with a 1-adamantane carbonyl moiety. The new synthesized compounds were tested for activities against some Gram-negative and Gram-positive bacteria, and the fungus . Compounds , , , and displayed potential antibacterial activity against tested Gram-positive bacteria and , while compounds and possessed cytotoxicity against tested human cancer cell lines.
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pham2019synthesismolecules Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Pham, Van Hien;Phan, Thi Phuong Dung;Phan, Dinh Chau;Vu, Binh Duong;
Journal molecules
Year 2019
DOI
E4000
URL
https://www.mdpi.com/1420-3049/24/21/4000
Keywords
Antimicrobial cytotoxicity activity adamantane derivatives hydrazide-hydrazone

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