COVID-19 - Considerations for the paediatric rheumatologist.

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ID: 104041
2020
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Ranked #6 of 22 articles by views in clinical immunology (orlando, fla)

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Abstract
The novel coronavirus SARS-CoV2 is a threat to the health and well-being of millions of lifes across the globe. A significant proportion of adult patients require hospitalisation and may develop severe life-threatening complications. Children, on the other hand, can carry and transmit the virus, but usually do not develop severe disease. Mortality in the paediatric age-group is relatively low. Differences in virus containment and clearance, as well as reduced inflammation-related tissue and organ damage may be caused by age-specific environmental and host factors. Since severe complications in adults are frequently caused by uncontrolled immune responses and a resulting "cytokine storm" that may be controlled by targeted blockade of cytokines, previously established treatment with immunosuppressive treatments may indeed protect children from complications.
Reference Key
hedrich2020covid19clinical Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Hedrich, Christian M;
Journal clinical immunology (orlando, fla)
Year 2020
DOI
S1521-6616(20)30259-X
URL
Keywords
inflammation rheumatology paediatric sars ards cytokine storm covid SARS-COV2

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