COVID-19 - Considerations for the paediatric rheumatologist.
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ID: 104041
2020
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Abstract
The novel coronavirus SARS-CoV2 is a threat to the health and well-being of millions of lifes across the globe. A significant proportion of adult patients require hospitalisation and may develop severe life-threatening complications. Children, on the other hand, can carry and transmit the virus, but usually do not develop severe disease. Mortality in the paediatric age-group is relatively low. Differences in virus containment and clearance, as well as reduced inflammation-related tissue and organ damage may be caused by age-specific environmental and host factors. Since severe complications in adults are frequently caused by uncontrolled immune responses and a resulting "cytokine storm" that may be controlled by targeted blockade of cytokines, previously established treatment with immunosuppressive treatments may indeed protect children from complications.
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| Reference Key |
hedrich2020covid19clinical
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| Authors | Hedrich, Christian M; |
| Journal | clinical immunology (orlando, fla) |
| Year | 2020 |
| DOI |
S1521-6616(20)30259-X
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