A new dynamic tool to perform assembly of expressed sequence tags (ESTs).

Clicks: 363
ID: 100916
1997
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Expressed Sequence Tags (ESTs) are short single-pass DNA sequences obtained from either ends of cDNA clones. To exploit these sequences efficiently, a dynamic Web-tool has been developed which uses these data to perform fast virtual cloning of cDNAs.Starting with a query sequence, the user is able to identify related ESTs and extend the sequence of interest step by step, possibly to a full-length transcript. Graphical views of the clustering are used to monitor the progress of a particular 'cloning' project. Potential open reading frames are detected by positional base preference, and hyperlinks to other Worldwide Web sites allows the user to retrieve information relevant to each EST in a cluster (e.g. sequence traces, clone size, plate position). Apart from cDNA cloning, this tool also provides a mechanism for collating gene families and polymorphism sites.
Reference Key
gill1997acomputer Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Gill, R W;Hodgman, T C;Littler, C B;Oxer, M D;Montgomery, D S;Taylor, S;Sanseau, P;
Journal computer applications in the biosciences : cabios
Year 1997
DOI
DOI not found
URL URL not found
Keywords
end-stage renal disease oxalosis primary hyperoxaluria consanguinity mutation analysis oxalate crystals oxalate stones pakistan origin

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.