Evaluation of a recombination-resistant coronavirus as a broadly applicable, rapidly implementable vaccine platform

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2018
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Abstract
Rachel Graham et al. show that coronaviruses with extensively rewired transcription regulatory networks are effective vaccine candidates against Severe Acute Respiratory Syndrome Coronavirus. The reversion of live-attenuated vaccine strains to virulence can be avoided with these vaccines.
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Authors Graham, Rachel L.;Deming, Damon J.;Deming, Meagan E.;Yount, Boyd L.;Baric, Ralph S.;
Journal Communications biology
Year 2018
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